Peanut Allergy is a food allergy to peanuts. The physical symptoms of allergic reaction are:
- asthma attack
- abdominal pain
- drop in blood pressure
- cardiac arrest
Cause of Peanut Allergy
Some of the peanut allergens can undergo enzymatic and non-enzymatic modifications which makes them more likely to bind to ligands on antigen-presenting cells. Ara h 1 can undergo glycosylation modifications which have been shown to induce immunomodulatory responses; it stimulates lectin receptors MR and DC-SIGN on dendritic cells which further propagate cytokines and bias the immune system towards a Th2 type response. Peanut proteins that undergo non-enzymatic changes through Maillard reactions when cooked or exposed to room temperature have an increase in AGE modifications on their structure. These changes have been shown to stimulate RAGE receptors and SR-AI/II on dendritic cells and thus lead to an increase in IL-4 and IL-5-releasing Th2 cells.
Peanut allergies are uncommon in children of undeveloped countries where peanut products have been used to relieve malnutrition. The hygiene hypothesis proposes that the relatively low incidence of childhood peanut allergies in undeveloped countries is a result of exposure to diverse food sources early in life, increasing immune capability, whereas food selection by children in developed countries is more limited, reducing immune capability. A possibility of cross-reaction to soy was dismissed by an analysis finding no linkage to consumption of soy protein, and indicated that appearance of any linkage is likely due to preference to using soy milk among families with known milk allergies.
To avoid a serious allergic reaction, work with a board-certified dermatologist to prevent a peanut allergy. Research shows it’s possible. You can prevent a person with eczema from developing a peanut allergy, but you’ll want to proceed carefully.